South San Francisco Real Estate

Welcome to South San Francisco, a vibrant city nestled in the heart of San Mateo County, California. Often referred to as “The Industrial City,” South San Francisco boasts a rich history and a dynamic blend of residential charm and economic vitality. With its picturesque views of the San Francisco Bay and the majestic San Bruno Mountain, this city offers a unique backdrop for both work and play.

One of South San Francisco's standout features is its exceptional accessibility. Conveniently located just minutes from downtown San Francisco, residents enjoy easy access to the bustling city while being able to retreat to the tranquility of their own community. The city is well-connected by major highways and public transportation, making it a prime location for commuters.

South San Francisco is not only about convenience; it is also a community that prides itself on diversity and inclusivity. With a variety of neighborhoods, each with its own unique character, potential homeowners can find everything from charming single-family homes to modern condos. The city is also home to excellent schools, parks, and recreational facilities, making it an ideal place for families to thrive.

Culturally rich, South San Francisco hosts numerous events throughout the year, including farmers' markets, festivals, and art walks, fostering a strong sense of community. Whether you're looking to explore the local dining scene, enjoy outdoor activities, or simply take in the stunning views, South San Francisco has something for everyone.

Discover the charm and opportunity that awaits in South San Francisco—a city where tradition meets innovation, and where you can truly feel at home.

Newest Listings in South San Francisco

$1,299,000

4 Beds ⋅ 3 Baths ⋅ ML82061001 MLS

Welcome to 13 Parkgrove Dr, an inviting Terrabay residence where generous interiors, abundant natural light, and peaceful hillside surroundings come together. This approx. 2,410 sq ft 4-bedroom home offers a thoughtful two-level floor plan with the space, flexibility, and comfort for everyday living and entertaining. From the moment you enter, expansive windows fill the home with natural light and create a wonderful sense of openness. The spacious family room, centered around a warm fireplace, flows seamlessly into the kitchen and dining area and continues to the living room, creating an inviting connection between the home's main gathering spaces. The 4-bedroom layout offers exceptional versatility and privacy, with room for guests, a home office, or spaces tailored to your lifestyle. Outside, the generous lot provides endless possibilities for outdoor enjoyment, from morning coffee and gardening to weekend gatherings. An attached 2-car garage adds convenience and storage. Set in the desirable Terrabay community, the home offers a peaceful residential setting with easy access to parks, shopping, dining, transportation, major commuter routes, and South San Francisco's renowned biotech and employment centers. Come experience what makes 13 Parkgrove Dr a special place to call home.

13 Parkgrove Drive, South San Francisco

Listing courtesy of from KW Advisors. 650-622-2156

$1,549,000

3 Beds ⋅ 2 Baths ⋅ ML82060428 MLS

Welcome to this spacious and versatile 3-bedroom, 2-bathroom home in South San Francisco. The open floor plan flows beautifully between the living, dining, and updated kitchen areas, creating the perfect setting for family gatherings and entertaining. The dining area also features a unique indoor BBQ grill. Off the garage is an additional room and full bathroom with a separate entrance, offering great flexibility for guests, extended family, a home office, or additional living space. Enjoy a large backyard with plenty of room for entertaining, gardening, or relaxing. Conveniently located near Highway 280, shopping plazas, restaurants, and more. A wonderful opportunity to make this versatile home your own!

328 Alta Mesa Drive, South San Francisco

Listing courtesy of Mouna Kayed from Compass. 650-784-1682

$1,598,000

5 Beds ⋅ 3 Baths ⋅ ML82060781 MLS

Welcome to 2231 Delvin Way, a beautifully maintained 5 BD, 3 BA home offering approximately 2,000 sqft in desirable Westborough. Thoughtfully updated while retaining its original charm, this inviting home ft refinished original hardwood floors & baseboards, plantation shutters, picturesque windows, fresh interior & exterior paint, updated electrical, and new light fixtures. An expansive LR welcomes you w/ recessed lighting, cozy fireplace, and charming partition separating the living & dining areas. The fully remodeled kitchen ft premium cabinetry, granite countertops, top-of-the-line SS appliances, and wine refrigerator. The open layout flows seamlessly into the family room, where sliding glass doors lead to low-maintenance backyard, ideal for relaxing & entertaining. Convenient main-level bedroom & full bathroom offer flexibility for guests, office, or multigenerational living. Upstairs 3 spacious guest bedrooms w/ new ceiling lights and generous primary suite w/ updated ensuite bathroom. Abundant closet space provides excellent storage. Completing the home is a 2-car garage. Meticulously cared for and move-in ready, this Westborough residence offers comfortable living and timeless appeal in a sought-after location, close to parks, shopping, dining, and everyday conveniences.

2231 Delvin Way, South San Francisco

Listing courtesy of from KW Advisors. 650-888-0153

$1,098,000

3 Beds ⋅ 1 Baths ⋅ ML82060772 MLS

Beautifully reimagined and move-in ready, 774 Alta Loma Dr offers modern style, thoughtful upgrades, and inviting single-story living in South San Francisco. This 3-bedroom, 1-bath home features approximately 1,220 sq ft of bright, refreshed living space designed for both comfort and everyday functionality. Step inside to discover new flooring and windows throughout, fresh interior paint, stylish lighting, and a beautifully renovated kitchen featuring new cabinetry, countertops, backsplash, and stainless steel appliances. The remodeled bathroom adds a fresh, contemporary touch to the home. Beyond its beautiful finishes, meaningful upgrades including a newly installed furnace and thermostat, updated electrical panel, new exterior and sliding glass doors, and a new garage door enhance comfort and functionality. Fresh exterior paint and updated landscaping enhance the homes curb appeal and create a welcoming first impression. Conveniently located near shopping, dining, parks, and major commute routes, this thoughtfully updated home brings together style, comfort, and convenience. This South San Francisco gem is not to be missed!

774 Alta Loma Drive, South San Francisco

Listing courtesy of from Aspire Homes. 408-320-8584

$998,000

2 Beds ⋅ 1 Baths ⋅ ML82060689 MLS

The best of Brentwood has just arrived! 214 Wildwood Dr. is one of those homes that has not just been lived in... it's been loved it's entire life! Meticulously maintained and renovated, this two-bedroom, one-bath home is freshly painted and features gleaming hardwood floors, a remodeled kitchen with the space and functionality for a world-class chef, a remodeled bathroom, a spacious yard for outdoor enjoyment, a large living room with fireplace, a dining room, and more that will have you ready to make this house your home! Enjoy plenty of on- and off-street parking, plus a one-car garage. Ideally located within easy walking distance of incredible shopping, dining, and transportation. This is not one of those homes you simply see... its a home you will feel! Make sure you don't miss it!

214 Wildwood, South San Francisco

Listing courtesy of Alex Lehr from Guide Real Estate. 650-766-5300

$719,000

1 Beds ⋅ 1 Baths ⋅ ML82060508 MLS

Experience elevated Bay Area living at The Mandalay View Retreat, a stunning 6th-floor residence where sweeping Bay and mountain views take center stage. An extra-large, est. 300 square foot private balcony creates the perfect setting for morning coffee, sunset cocktails, or simply enjoying the scenery. Inside, the bright open-concept living and dining areas feature high ceilings, crown molding and newer laminate flooring. The stylish kitchen offers designer cabinetry, granite countertops and premium appliances, while a versatile alcove is ideal for a home office or reading retreat. Enjoy the convenience of an in-unit washer & dryer, 2 dedicated parking spaces, secure storage and guest parking. Resort-inspired amenities include a fitness center, business lounge, clubroom and scenic patio, plus secured key-fob access and package room. Ideally located near Hwy 101 for easy access to San Francisco, Silicon Valley and SFO, with Marina Park and San Bruno Mountain Ridge trails nearby. Exceptional views, space and amenities; all awaiting you. Perfect for daily living and family gatherings. Schedule your private tour and make this remarkable residence yours!

1 Mandalay Place Unit #603, South San Francisco

Listing courtesy of Alan Canas from Engel & Voelkers Burlingame. 415-298-8940

$1,680,000

3 Beds ⋅ 3 Baths ⋅ ML82059726 MLS

This expansive 3,160 sq. ft. single-family home sits in convenient South San Francisco with beautiful partial mountain views. It features an updated kitchen, partially refreshed baths, and two flexible bonus rooms ready to serve as an office, gym, nursery, theater, or extra bedrooms. The open floor plan is designed for relaxed everyday living, with a formal dining room well suited to entertaining. A rare extra-large 3-car garage (not included in the square footage) and washer and dryer connections on both the main floor and in the garage add to everyday convenience. Substantial living space and Peninsula convenience in one package. Welcome to your new home!

541 Chestnut Avenue, South San Francisco

Listing courtesy of Eric Lin from KW Advisors. 415-690-8434

$998,888

2 Beds ⋅ 1 Baths ⋅ ML82060106 MLS

Located in South San Francisco, this 2-bedroom, 1-bathroom home offers 1,050 sq ft of living space on a 4,675 sq ft lot. The ground floor bedroom and laminate flooring throughout provide a practical layout. The kitchen features modern appliances including a dishwasher, garbage disposal, electric oven, and refrigerator. The bathroom includes a primary stall shower with tile finishes. The living room is enhanced by a fireplace, adding a cozy focal point to the space. Laundry facilities include an electricity hookup (110V). Additional interior features include a dining area and a video/audio system. The property includes a one-car garage and is located within the South San Francisco Unified elementary school district. No cooling system or pool is present.

208 Camaritas Avenue, South San Francisco

Listing courtesy of Bessie Marfori from Intero Real Estate Services. 650-483-2281

$699,000

1 Beds ⋅ 1 Baths ⋅ ML82060038 MLS

High Rise Luxury Living at its finest. Million Dollar Views of the Bay and City Lights. Unbeatable location-very close to SF, the new Biotech hub in SSF, SFO, BART, 101/280. Bright and open living space. Modern kitchen with gas stove, stainless steel appliances, granite countertops. The large master bedroom also has panoramic views! Additional highlights include an in-unit washer/dryer, 2 assigned parking spaces & a secured storage locker. Located in a secure high-rise building, residents enjoy access to a fitness center, a social room, community terrace, elegant lobby & visitor parking. Close to restaurants along Downtown SSFs Grand Ave.

1 Mandalay Place Unit #805, South San Francisco

Listing courtesy of Christine Rosenfeld from Compass. 650-270-9397

$1,478,000

3 Beds ⋅ 2 Baths ⋅ ML82059340 MLS

Beautifully refreshed and thoughtfully expanded, this impressive 3-bedroom, 2-bath residence offers approximately 1,870 square feet of inviting living space designed for both everyday comfort and effortless entertaining. A fresh interior and exterior color palette creates a crisp, sophisticated feel, complemented by newly installed and beautifully refinished hardwood flooring throughout. The updated kitchen features new countertops and appliances, offering a stylish and functional centerpiece for the home. Expanded over the years, the residence offers a wonderfully versatile floor plan with a spacious family room and enclosed patio providing additional areas to gather, entertain or simply unwind. Generous living spaces and an easy flow throughout the home create a sense of openness rarely found in a traditional three-bedroom residence. The transformation continues outdoors, where newly landscaped front and rear yards enhance the homes curb appeal and create attractive settings for outdoor dining, entertaining and relaxation. Freshly updated, exceptionally spacious and ready to enjoy, 343 Alta Mesa Drive presents a wonderful opportunity to experience elevated Peninsula living with the space and flexibility to make it truly your own.

343 Alta Mesa Drive, South San Francisco

Listing courtesy of Stephan A. Marshall from Christie's International Real Estate Sereno. 650-455-1528

$1,248,000

3 Beds ⋅ 4 Baths ⋅ ML82059314 MLS

Ideally located near Downtown South San Francisco and the cities thriving biotech and life-sciences corridor, 643 Grand Avenue where space, comfort, and a remarkable garden setting come together in the heart of South San Francisco. 643 Grand Avenue offers a spacious and versatile layout with excellent access to major transportation and employment centers. The home features 3 bedrooms and 4 bathrooms, with a private full bathroom for each bedroom. Additional highlights include high ceilings, abundant natural light, hardwood floors, a full basement with ample storage, and a detached 2-car garage equipped with a 220-volt outlet for EV charging. The home also features a water purification system, tankless water heater, and water softener. The quaint lot includes a freshly manicured organic vegetable garden with sunflowers and offers potential for an ADU. Conveniently located near Downtown South San Francisco, Genentech, Caltrain, US-101, and I-280.

643 Grand Avenue, South San Francisco

Listing courtesy of Jill Penna from Christie's International Real Estate Sereno. 415-244-8630

$924,800

2 Beds ⋅ 2 Baths ⋅ ML82059246 MLS

Set against the scenic backdrop of San Bruno Mountain Ecological Reserve, well-maintained 2 BD, 2 BA corner penthouse offers 1,440 sqft of modern high-rise elegance w/ soaring ceilings. The grand lobby ft. a dazzling chandelier and sunlit lounge. Inside, open living & dining area is flooded w natural light, framed by sweeping mountain views through oversized windows. Hardwood floors run throughout, while plush carpet in the bedrooms adds warmth. The chef-inspired kitchen ft designer cabinetry, granite counters, and stainless steel appliances. The primary suite includes a walk-in closet with custom organization and a spacious bathroom. The second bedroom offers a comfortable, private feel, and an in-unit washer & dryer adds convenience. Additional perks: 2 dedicated parking spaces, guest parking, and access to fitness center, business center, clubroom, and landscaped patio. Key fob entry and a package room add security. As a corner unit, the home benefits from added natural light and extra windows. Location is unbeatable, minutes from Highway 101, with Costco, Oyster Point dining, and Marina Park's waterfront paths nearby. The San Bruno Mountain Ridge Trail begins right outside your door elevated comfort, timeless style, and one of the best lifestyles the Bay Area has to offer.

1 Mandalay Place Unit #1510, South San Francisco

Listing courtesy of from KW Advisors. 650-888-0153

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